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Supplements

Longevity supplements, reviewed honestly.

NMN, NR, resveratrol, spermidine, magnesium, omega-3, and the rest of the modern longevity stack. We test for purity, bioavailability, and value per dose. No "miracle pill" hype — just what the evidence supports and what's worth your money.

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Best NMN Supplements

Renue, ProHealth, OMRE, and Double Wood compared on purity, dose, bioavailability, and value.

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Best NR (Nicotinamide Riboside) Supplements

Tru Niagen, Renue, Elysium Basis. The other NAD+ precursor, explained.

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Best Resveratrol Supplements

NOW, OMRE, and other top resveratrol brands. Why micronized matters and what to avoid.

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Best Spermidine Supplements

10mg synthetic vs wheat-germ extract. The autophagy-inducing supplement Peter Attia takes.

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Best Astaxanthin Supplements

The underrated carotenoid antioxidant. Why 12mg is the dose used in clinical studies.

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Best Magnesium Supplements

Glycinate, citrate, malate, threonate — which form is right for sleep, energy, or brain?

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Best Magnesium Threonate

The only magnesium that crosses the blood-brain barrier. MIT research on cognitive function.

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Best Vitamin D3 + K2 Supplements

Why you need both D3 and K2 together. Liquid vs capsule, MK-4 vs MK-7 explained.

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Best Omega-3 Supplements

Nordic Naturals, Sports Research, Nature Made. Triglyceride vs ethyl ester — what matters.

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Best Creatine Supplements

Not just for bodybuilders — creatine is one of the most evidence-based longevity supplements.

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Best Apigenin Supplements

Huberman's sleep stack. 50mg of apigenin for relaxation and sleep quality.

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Best Adaptogens for Stress

Ashwagandha, rhodiola, and the supplements that actually lower cortisol.

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Best Curcumin Supplements

Turmeric curcumin with BioPerine. Anti-inflammatory powerhouse with 20x absorption.

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Best CoQ10 Supplements

Ubiquinol vs ubiquinone. Why CoQ10 matters more after 40 and on statins.

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Best Probiotics

50-60 billion CFU probiotics compared. Strain diversity, delayed-release, prebiotics.

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Best Collagen Supplements

Vital Proteins collagen peptides with hyaluronic acid and vitamin C.

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Best Fisetin Supplements

Senolytic flavonoid that clears zombie cells. Periodic dosing protocol explained.

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Best Quercetin Supplements

Quercetin + bromelain combo for inflammation, allergies, and senolytic synergy.

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Best Berberine Supplements

Berberine HCL — the natural metformin alternative. AMPK activator for blood sugar.

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Best Lion's Mane Supplements

Fruiting body vs mycelium. Cognitive support and nerve growth factor (NGF).

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Best L-Theanine Supplements

200mg L-theanine for calm focus. The perfect caffeine companion.

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Best Glycine Supplements

Glycine for sleep, collagen synthesis, and glutathione production.

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Best Taurine Supplements

The underrated amino acid that extended mouse lifespan by 10-12%.

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Best NAC Supplements

N-Acetyl Cysteine — the glutathione precursor for liver, lung, and brain health.

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Best Multivitamins for Longevity

Thorne Men's and Women's Multi 50+. Methylated B vitamins, third-party certified.

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David Sinclair's Supplement List

The Harvard researcher's full daily stack, decoded and explained.

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Bryan Johnson's Blueprint Protocol

The $2M/year anti-aging protocol, broken down step by step.

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NMN vs NR: Which NAD+ Booster Wins?

The two leading NAD+ precursors, head-to-head.

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NAD+ Explained: The Molecule Behind Longevity

Why NAD+ matters, how it declines with age, and how to restore it.

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Longevity Supplement Stack Guide

How to combine supplements for synergy — and what never to mix.

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Best Supplements for Cognitive Health

Lion's mane, bacopa, omega-3, mag threonate — brain optimization stack.

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Best Supplements for Joint Health

Collagen, omega-3, curcumin, boswellia — the joint health stack.

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Best Supplements for Energy

CoQ10, B-complex, rhodiola — energy supplements beyond caffeine.

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Best Supplements for Skin Anti-Aging

Collagen, hyaluronic acid, vitamin C, astaxanthin — skin health from within.

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Best Supplements for Heart Health

Omega-3, CoQ10, magnesium, berberine — cardiovascular longevity stack.

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Rapamycin for Longevity: A Complete Guide

The most controversial longevity drug. What the science says about low-dose rapamycin.

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Metformin for Longevity: What We Know

The diabetes drug being studied for anti-aging. TAME trial, dosing, and risks.

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